Tenascin C is an anti-adhesive protein that may in fact break down existing retinoschisin. So far,this protein has not been found in any other structure in the normal vitreous cavity or in the vitreous cavity of children affected with congenital X-linked retinoschisis. The implications of Tenascin C and possible therapeutic interventions have not yet been described.

This protein, however, does seem to raise a question as to whether or not even adequately adhesive retinoschisin may be broken down leading to the splitting of the retina and reduction in vision that is seen in congenital retinoschisis. This allows a potentially new therapeutic direction for this potentially blinding disease.